loss-of-heterozygosity

loss-of-heterozygosity
потеря гетерозиготности

English-Russian Biotechnology Glossary. . 2007.

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Смотреть что такое "loss-of-heterozygosity" в других словарях:

  • Loss of heterozygosity — (LOH) in a cell represents the loss of normal function of one allele of a gene in which the other allele was already inactivated. This term is mostly used in the context of oncogenesis; after an inactivating mutation in one allele of a tumor… …   Wikipedia

  • loss-of-heterozygosity — loss of heterozygosity. См. потеря гетерозиготности. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • loss of heterozygosity — (LOH) loss of the allele from one chromosome of a pair, as by deletion, nondisjunction, mitotic recombination, or suppression of function, so that the locus is converted from heterozygosity to homozygosity or hemizygosity; it is often associated… …   Medical dictionary

  • LOH — Loss of Heterozygosity (Medical » Oncology) Loss Of Heterozygosity (Medical » Human Genome) * Line Overhead (Computing » Telecom) * Light Observation Helicopter (Governmental » Transportation) * Loja, Ecuador (Regional » Airport Codes) …   Abbreviations dictionary

  • потеря гетерозиготности — loss of heterozygosity “потеря гетерозиготности”. Сокращение изменчивости в участках генома, для которых обычно характерен полиморфизм длин рестрикционных фрагментов <restriction fragment length polymorphism>; в клинической генетике эффект… …   Молекулярная биология и генетика. Толковый словарь.

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  • Somatic evolution in cancer — Somatic evolution is the accumulation of mutations in the cells of a body (the soma) during a lifetime, and the effects of those mutations on the fitness of those cells. Somatic evolution is important in the process of aging as well as the… …   Wikipedia

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